https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Clinical outcomes in transient epileptic amnesia: A 10-year follow-up cohort study of 47 cases https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48090 Wed 28 Jun 2023 18:56:58 AEST ]]> Thrombolysis implementation intervention and clinical outcome: a secondary analysis of a cluster randomized trial https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42696 Tue 14 Nov 2023 14:44:08 AEDT ]]> A comprehensive analysis of metabolic changes in the salvaged penumbra https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:23095 Thu 28 Oct 2021 12:36:41 AEDT ]]> Mediation of Successful Reperfusion Effect through Infarct Growth and Cerebral Edema: A Pooled, Patient-Level Analysis of EXTEND-IA Trials and SELECT Prospective Cohort https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:52653 Thu 19 Oct 2023 15:25:33 AEDT ]]> Prehospital notification procedure improves stroke outcome by shortening onset to needle time in Chinese urban area https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41242 Sat 30 Jul 2022 12:26:18 AEST ]]> Cognitive elements in clinical decision-making: toward a cognitive model for medical education and understanding clinical reasoning https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:9429 Sat 24 Mar 2018 10:47:55 AEDT ]]> Multicomponent, home-based resistance training for obese adults with type 2 diabetes: a randomized controlled trial https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:9382 Sat 24 Mar 2018 10:45:36 AEDT ]]> Perfusion computer tomography: imaging and clinical validation in acute ischaemic stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17430 2 s was the most accurate computed tomography perfusion threshold in predicting the extent of critically hypoperfused tissue with both receiver operating curve analysis (area under curve 0.86), and the volumetric validation (mean difference between computed tomography perfusion and 24-h diffusion-weighted imaging lesions = 2 cm², 95% confidence interval 0.5–3.2 cm²). Cerebral blood flow <40% (of contralateral) within the relative delay time >2 s perfusion lesion was the most accurate computed tomography perfusion threshold at defining infarct core with both receiver operating characteristic analysis (area under curve = 0.85) and the volumetric validation. Using these thresholds, the extent of computed tomography perfusion mismatch tissue (the volume of ‘at-risk’ tissue between the critically hypoperfused and core thresholds) salvaged from infarction correlated with clinical improvement at 24 h (R² = 0.59, P = 0.04) and 90 days (R² = 0.42, P = 0.02). Patients with larger baseline computed tomography perfusion infarct core volume (>25 ml) also had poorer recovery at Day 90 (P = 0.039). Computed tomography perfusion can accurately identify critically hypoperfused tissue that progresses to infarction without early reperfusion, and the computed tomography perfusion cerebral blood flow infarct core closely predicts the final volume of infarcted tissue in patients who do reperfuse. The computed tomography perfusion infarct core and at-risk measures identified are also strong predictors of clinical outcome.]]> Sat 24 Mar 2018 08:01:40 AEDT ]]> The influence of anterior cerebral artery flow diversion measured by transcranial Doppler on acute infarct volume and clinical outcome in anterior circulation stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19935 Sat 24 Mar 2018 07:58:30 AEDT ]]> A multicenter randomized trial of continuous versus intermittent β-lactam infusion in severe sepsis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24441 Sat 24 Mar 2018 07:17:27 AEDT ]]> Arterial spin labeling identifies tissue salvage and good clinical recovery after acute ischemic stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:23590 Sat 24 Mar 2018 07:13:22 AEDT ]]>